| EX0629 FACTOR VIII FUNCTIONAL / ACTIVITY |
| Specimen: |
3 mL whole blood in 1 Blue Top (Sodium Citrate) tube. Mix thoroughly by inversion. Transport to Lab within 4 hours. If this is not possible, make PPP within 1 hour of the collection as follows: Centrifuge sample at 3600 rpm for 15 min. & transfer supernatant to a clean plastic tube. Centrifuge this supernatant again at 3600 rpm for 15 mins. & finally, transfer the supernatant (PPP) to 1 labeled clean plastic screw-capped vial. FREEZE IMMEDIATELY. Ship frozen. DO NOT THAW. |
| Stability: |
| Room |
Refrigerated |
Frozen |
| 4 hrs |
4 hrs |
2 weeks |
|
| Method: |
Electromechanical Clot Detection |
| Comment: |
It is recommended that the patient discontinues Heparin for 1 day and Oral Anticoagulants for 7 days prior to sampling as these drugs may affect test results. Discontinuation should be with prior consent from the treating Physician. |
| Report: |
Contact us to know the TAT. |
| Usage: |
Deficiency of Factor VIII causes prolongation of APTT that corrects completely on mixing. Congenital Factor VIII deficiency is called Hemophilia A which is inherited in an X-linked recessive manner. It affects 1 per 5000 to 10000 live male births. Males are affected whereas females are carriers. The severe form generally presents in infancy with spontaneous bleeding in soft tissues, joints, or intracranial/urinary/gastrointestinal bleeding. Factor VIII is also decreased in moderate & severe forms of von Willebrand disease (VWD). |
| Doctor Specialty: |
Hematologist |
| Disease: |
Disorders of Coagulation |
| Components: |
|
| Courier Charges: |
0.00 |
| Home Collection: |
Available (*T&C Apply) |
| Department: |
Coagulation |
| Pre Test Information: |
Overnight fasting is preferred. A duly filled Coagulation Requisition Form is mandatory. It is recommended that the patient discontinues Heparin for 1 day and Oral Anticoagulants for 7 days prior to sampling as these drugs may affect test results. Discontinuation should be with prior consent from the treating Physician. |
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