| EX2087 ZnT8 (ZINC TRANSPORTER 8) ANTIBODY |
| Specimen: |
3 mL (2 mL min.) Serum from 1 SST. Ship refrigerated or frozen. |
| Stability: |
| Room |
Refrigerated |
Frozen |
| 8 hrs |
72 hrs |
4 weeks |
|
| Method: |
EIA |
| Comment: |
See DIABETES TYPE 1 AUTOIMMUNE PROFILE. |
| Report: |
Contact us to know the TAT. |
| Usage: |
Zinc transporter 8 (ZnT8) is an islet beta-cell secretory granule membrane protein recently identified as an autoantibody antigen in Type 1 Diabetes. ZnT8 autoantibodies are present in around 65 to 80% of children with recently diagnosed Type 1 Diabetes and 20% to 40% of adults with Type 1 diabetes. ZnT8 antibody complements GAD-65, IA-2, and insulin antibodies as it is positive in 3% to 4% of patients who are negative for GAD-65, IA-2, and insulin antibodies. The use of these 4 antibodies results in 93% to 98% sensitivity. ZnT8 antibody testing can be considered for the clinical distinction of Type 1 from Type 2 Diabetes Mellitus, identification of individuals at risk of Type 1 Diabetes (including high-risk relatives of patients with diabetes, and those with Gestational Diabetes) & prediction of future need for insulin treatment in adult-onset diabetic patients. |
| Doctor Specialty: |
Diabetologist |
| Disease: |
Diabetes |
| Components: |
|
| Courier Charges: |
|
| Home Collection: |
Available (*T&C Apply) |
| Department: |
IMMUNOASSAY |
| Pre Test Information: |
No special preparation required |
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