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| Laboratory | Exult Diagnostics, Dr. Lal PathLabs |
|---|
₹ 4000
| EX2087 ZnT8 (ZINC TRANSPORTER 8) ANTIBODY | |||||||
| Specimen: | 3 mL (2 mL min.) Serum from 1 SST. Ship refrigerated or frozen. | ||||||
| Stability: |
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| Method: | EIA | ||||||
| Comment: | See DIABETES TYPE 1 AUTOIMMUNE PROFILE. | ||||||
| Report: | Contact us to know the TAT. | ||||||
| Usage: | Zinc transporter 8 (ZnT8) is an islet beta-cell secretory granule membrane protein recently identified as an autoantibody antigen in Type 1 Diabetes. ZnT8 autoantibodies are present in around 65 to 80% of children with recently diagnosed Type 1 Diabetes and 20% to 40% of adults with Type 1 diabetes. ZnT8 antibody complements GAD-65, IA-2, and insulin antibodies as it is positive in 3% to 4% of patients who are negative for GAD-65, IA-2, and insulin antibodies. The use of these 4 antibodies results in 93% to 98% sensitivity. ZnT8 antibody testing can be considered for the clinical distinction of Type 1 from Type 2 Diabetes Mellitus, identification of individuals at risk of Type 1 Diabetes (including high-risk relatives of patients with diabetes, and those with Gestational Diabetes) & prediction of future need for insulin treatment in adult-onset diabetic patients. | ||||||
| Doctor Specialty: | Diabetologist | ||||||
| Disease: | Diabetes | ||||||
| Components: | |||||||
| Courier Charges: | |||||||
| Home Collection: | Available (*T&C Apply) | ||||||
| Department: | IMMUNOASSAY | ||||||
| Pre Test Information: | No special preparation required | ||||||
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