| EX2061 VITAMIN B1 (THIAMINE PYROPHOSPHATE), BLOOD |
| Specimen: |
3 mL (2 mL min.) Whole blood from 1 Lavender Top (EDTA) tube wrapped completely with black paper or aluminum foil. Ship refrigerated or frozen. Uncovered tubes exposed to light are unacceptable. |
| Stability: |
| Room |
Refrigerated |
Frozen |
| 6 HRS |
24 HRS |
30 DAYS |
|
| Method: |
LC-MS/MS |
| Comment: |
For the assessment of the vitamin B1 status, the direct measurement of TPP by HPLC is considered the method of choice because of better sensitivity and specificity. |
| Report: |
Contact us to know the TAT. |
| Usage: |
Vitamin B1 (Thiamine) is an essential vitamin required for carbohydrate metabolism. It is converted in the intestine to Thiamine pyrophosphate (TPP) which is the active form of Vitamin B1. The high-risk factors for thiamine deficiency include old age, long-term parenteral nutrition, hemodialysis, malabsorption, or alcohol abuse. Severe deficiency causes congestive heart failure (wet beriberi), peripheral neuropathy (dry beriberi), Wernicke encephalopathy (a medical emergency that can progress to coma and death), and Korsakoff syndrome (often irreversible memory loss and dementia that can follow). |
| Doctor Specialty: |
Physician |
| Disease: |
Disorders of Nutrition |
| Components: |
|
| Courier Charges: |
0.00 |
| Home Collection: |
Available (*T&C Apply) |
| Department: |
HPLC |
| Pre Test Information: |
Wrap sample in aluminum foil to protect from light. |
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