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Laboratory

Exult Diagnostics, Dr. Lal PathLabs, Metropolis Labs, Oncquest Labs

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UGT1A1 GENE POLYMORPHISM (NUCLEOTIDE ‘TA’ REPEATS) DETECTION

 5500 6600

EX2012      UGT1A1 GENE POLYMORPHISM (NUCLEOTIDE ‘TA’ REPEATS) DETECTION
Specimen: 4 mL (2 mL min.) whole Blood in 1 Lavender top (EDTA) tube. Ship refrigerated. DO NOT FREEZE.
Stability:
Room Refrigerated Frozen
8 hrs 1 week NA
Method: PCR, Fragment analysis
Comment:
Report: Contact us to know the TAT.
Usage: Genetic variants in UGT1A1 may cause reduced or absent UGT1A1 enzymatic activity, resulting in conditions associated with unconjugated hyperbilirubinemia including Gilbert syndrome and Crigler-Najjar syndromes types I and II. Gilbert syndrome is the most common hereditary cause of increased bilirubin. This assay also helps in identifying individuals who are at increased risk of adverse reactions to drugs that are metabolized by UGT1A1 including Irinotecan, Atazanavir, Nilotinib, Pazopanib, and Belinostat.
Doctor Specialty: Gastroenterologist, Oncologist
Disease: Disorders of Liver, Pharmacogenomics
Components:
Courier Charges:
Home Collection: Available (*T&C Apply)
Department: MOLECULAR DIAGNOSTICS
Pre Test Information: No special preparation required