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Laboratory

Exult Diagnostics, Dr. Lal PathLabs, Metropolis Labs, Oncquest Labs, Pathkind Labs

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TUMOR NECROSIS FACTOR (TNF) ALPHA

 3900 5450

EX2004      TUMOR NECROSIS FACTOR (TNF) ALPHA
Specimen: 2 mL (1 mL min.) serum from 1 SST. Ship refrigerated or frozen.
Stability:
Room Refrigerated Frozen
2 hrs 48 hrs 4 weeks
Method: Chemiluminescent Immunoassay
Comment:
Report: Contact us to know the TAT.
Usage: Tumor necrosis factor (TNF)-alpha is expressed primarily by activated monocytes as part of the innate immune response to various microbes, gram-negative bacteria in particular. Its function is to recruit other leukocytes to the site of infection and stimulate their activation. TNF-alpha also has some systemic effects, including induction of fever through action on the hypothalamus. In cases of severe gram-negative bacterial infection, Septic shock can occur characterized by hypotension, disseminated intravascular coagulation, tachycardia & increased respiration, and can be fatal. Dysregulation of TNF-alpha expression is thought to be a critical pathogenic mechanism in numerous autoimmune diseases, including Inflammatory bowel disease (IBD), Rheumatoid arthritis (RA), and Ankylosing spondylitis (AS). TNF-alpha is used for the evaluation of patients with suspected systemic infection, particularly caused by gram-negative bacteria & for the evaluation of patients with suspected chronic inflammatory disorders.
Doctor Specialty: Nephrologist
Disease: Transplantation Pathology
Components:
Courier Charges: 0.00
Home Collection: Available (*T&C Apply)
Department: Biochemistry
Pre Test Information: No special preparation required