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| Laboratory | Exult Diagnostics, Dr. Lal PathLabs |
|---|
₹ 21500
| EX1957 THROMBOPHILIA TOTAL PROFILE | |||||||
| Specimen: | 6 mL whole blood in 2 Blue Top (Sodium Citrate) tubes. Mix thoroughly by inversion. Transport to Lab within 4 hours. If this is not possible, make PPP within 1 hour of the collection as follows: Centrifuge sample at 3600 rpm for 15 min. & transfer supernatant to a clean plastic tube. Centrifuge this supernatant again at 3600 rpm for 15 mins. & finally, transfer the supernatant (PPP) to 1 labeled clean plastic screw-capped vial. FREEZE IMMEDIATELY. Ship frozen. DO NOT THAW. AND 3 mL (2 mL min.) whole blood in 1 Lavender Top (EDTA) tube. Ship refrigerated AND 3 mL (1 mL min.) serum from 1 SST. | ||||||
| Stability: |
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| Method: | Chromogenic Assay, Electromechanical Clot Detection, Photo-optical Clot Detection, Immunoturbidimetry, EIA, Real-Time PCR, CMIA | ||||||
| Comment: | Samples received on holidays will be reported in the next schedule/next working day. | ||||||
| Report: | Contact us to know the TAT. | ||||||
| Usage: | Thrombophilia evaluations are usually performed to assess the need to extend anticoagulation, hence testing should be performed in a steady-state, remote from the acute event. Laboratory assays to detect thrombophilic states include highly sensitive and specific tests like molecular diagnosis, immunologic and functional assays. Many coagulation factors and inhibitors are affected during acute thrombosis, acute illnesses, inflammatory conditions, pregnancy certain medications. Antithrombin is decreased by heparin and acute thrombosis whereas protein C & S levels are increased during acute thrombosis, but decreased by warfarin. Antiphospholipid antibodies like lupus anticoagulants, anticardiolipin antibodies & anti-beta 2 glycoprotein antibodies are also associated with thromboembolic disease states. Higher levels of factor VIII (>150%), factor V Leiden mutations, and increased homocysteine levels are also associated with an increased risk of thromboembolic disease. | ||||||
| Doctor Specialty: | Hematologist | ||||||
| Disease: | Disorders of Coagulation | ||||||
| Components: | *Protein C, Functional *Protein S Antigen, Free *Antithrombin Activity Functional *Mixing studies APTT *Lupus anticoagulant panel | ||||||
| Courier Charges: | |||||||
| Home Collection: | Available (*T&C Apply) | ||||||
| Department: | COAGULATION | ||||||
| Pre Test Information: | Overnight fasting is preferred. A duly filled Coagulation Requisition Form is mandatory. It is recommended that the patient discontinues Heparin for 1 day and Oral Anticoagulants for 7 days prior to sampling as these drugs may affect test results. Discontinuation should be with prior consent from the treating Physician. | ||||||
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