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Laboratory

Exult Diagnostics, Dr. Lal PathLabs

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t(4;11) (q21;q23); (MLL-AF4) PCR QUALITATIVE

 3200

EX1919      t(4;11) (q21;q23); (MLL-AF4) PCR QUALITATIVE
Specimen: 3 mL (2 mL min.) whole blood / Bone marrow in 1 Lavender Top (EDTA) tube. Ship refrigerated. DO NOT FREEZE. Clinical history is mandatory.
Stability:
Room Refrigerated Frozen
6 hrs 72 hrs NA
Method: Real-Time PCR
Comment: Samples received on holidays will be reported in the next schedule/next working day.
Report: Contact us to know the TAT.
Usage: Chromosomal rearrangements can produce tumorigenic fusion genes. This mechanism is seen in 15-25% of Leukemias, Lymphomas & Sarcomas. Fusions can be produced by translocations, inversions, or deletions. Specific gene fusions in a patient’s tumor cells have an important bearing on the management & prognosis. This translocation results in the MLL- AF4 fusion gene and is associated with a poor outcome. It is found in >80% cases of infant ALL and is the most frequent MLL translocation in ALL but is rarely seen in AML.
Doctor Specialty: Oncologist
Disease: Leukemia
Components:
Courier Charges: 0.00
Home Collection: Available (*T&C Apply)
Department: MOLECULAR DIAGNOSTICS
Pre Test Information: Clinical history is mandatory.