| EX1916 t(1;19) (q23;p13.3); TCF3- BX1(E2A-PBX1) PCR QUALITATIVE |
| Specimen: |
3 mL (2 mL min.) whole blood / Bone marrow in 1 Lavender Top (EDTA) tube. Ship refrigerated. DO NOT FREEZE. Clinical history is mandatory. |
| Stability: |
| Room |
Refrigerated |
Frozen |
| 6 hrs |
72 hrs |
NA |
|
| Method: |
Real-Time PCR |
| Comment: |
Samples received on holidays will be reported in the next schedule/next working day. |
| Report: |
Contact us to know the TAT. |
| Usage: |
Chromosomal rearrangements can produce tumorigenic fusion genes. This mechanism is seen in 15-25% of Leukemias, Lymphomas & Sarcomas. Fusions can be produced by translocations, inversions, or deletions. Specific gene fusions in a patient’s tumor cells have an important bearing on the management & prognosis. Detection of translocation t(1;19) in Acute Lymphoblastic leukemia (ALL) may be balanced or unbalanced. Both are associated with poor prognosis but more so if you have an unbalanced translocation. Such patients are usually children with T-ALL and require intensive chemotherapy to control the disease. |
| Doctor Specialty: |
Oncologist |
| Disease: |
Leukemia |
| Components: |
|
| Courier Charges: |
0.00 |
| Home Collection: |
Available (*T&C Apply) |
| Department: |
MOLECULAR DIAGNOSTICS |
| Pre Test Information: |
Clinical history is mandatory. |
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