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Laboratory

Exult Diagnostics, Dr. Lal PathLabs, Metropolis Labs, Oncquest Labs, Pathkind Labs

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PLASMA RENIN, DIRECT

 3400 5200

EX1719      PLASMA RENIN, DIRECT
Specimen: 3 mL (2.5 mL min.) plasma from 1 Lavender Top (EDTA) tube.
Stability:
Room Refrigerated Frozen
NA NA 4 weeks
Method: CLIA
Comment: Also see ANGIOTENSIN II.
Report: Contact us to know the TAT.
Usage: Renin is a proteolytic enzyme released from juxtaglomerular cells of the kidney. The enzyme cleaves a substrate to produce Angiotensin I which in turn produces Angiotensin II. This metabolite plays a key role in various forms of hypertension. Increased levels are seen in Renal hypertension, Addison’s disease, and Secondary hypoaldosteronism. Low levels are detected in Hyporeninemic hypoaldosteronism and Primary aldosteronism.
Doctor Specialty: Nephrologist
Disease: Disorders of Kidney
Components:
Courier Charges: 0.00
Home Collection: Available (*T&C Apply)
Department: Biochemistry
Pre Test Information: The patient should be ambulatory/upright 2 hours prior to the test. Drug interactions to be noted: Potassium wasting diuretics, Spironolactone, Eplerenone, Amiloride, and Triamterene should be discontinued for at least for 4 weeks; Adrenergic blockers, Clonidine, Methyldopa, NSAIDs, Angiotensin-converting enzyme inhibitors, Angiotensin receptor blockers, Renin inhibitors, and Dihydropyridine calcium channel antagonists should be discontinued for 2 weeks. If necessary to maintain hypertension control, patients should be treated with other antihypertensive medications like Verapamil slow-release, Hydralazine, Prazosin, Doxazosin & Terazosin that have lesser effects on Plasma renin levels. Any change in medication should be done in consultation with the treating clinician.