| EX1521 MIXING STUDIES – APTT WITH PROTHROMBIN TIME STUDIES |
| Specimen: |
6 mL whole blood in 2 Blue Top (Sodium Citrate) tubes. Mix thoroughly by inversion. Transport to Lab within 4 hours. If this is not possible, make PPP within 1 hour of the collection as follows: Centrifuge sample at 3600 rpm for 15 min. & transfer supernatant to a clean plastic tube. Centrifuge this supernatant again at 3600 rpm for 15 min. & finally, transfer the supernatant (PPP) to 1 labeled clean plastic screw-capped vial. FREEZE IMMEDIATELY. Ship frozen. DO NOT THAW. |
| Stability: |
| Room |
Refrigerated |
Frozen |
| 4 hrs |
4 hrs |
2 weeks |
|
| Method: |
Photo-optical Clot Detection |
| Comment: |
It is recommended that the patient discontinues Heparin for 1 day and Oral Anticoagulants for 7 days prior to sampling as these drugs may affect test results. Discontinuation should be with prior consent from the treating Physician. |
| Report: |
Contact us to know the TAT. |
| Usage: |
Correction of a prolonged PT/APTT with mixing generally implies a qualitative or quantitative abnormality of one or more clotting factors in the patient’s plasma. In contrast, failure of PT/APTT to correct completely on mixing suggests the presence of inhibitors in the patient’s plasma eg. Lupus anticoagulants (LA) & inhibitors to specific clotting factors. Occasionally a weak LA may produce a prolonged PT or APTT that corrects on mixing. |
| Doctor Specialty: |
Hematologist |
| Disease: |
Disorders of Coagulation |
| Components: |
*Prothrombin Time *APTT *Thrombin Time *Fibrinogen *Mixing studies |
| Courier Charges: |
0.00 |
| Home Collection: |
Available (*T&C Apply) |
| Department: |
Coagulation |
| Pre Test Information: |
Overnight fasting is preferred. A duly filled Coagulation Requisition Form is mandatory. It is recommended that the patient discontinues Heparin for 1 day and Oral Anticoagulants for 7 days prior to sampling as these drugs may affect test results. Discontinuation should be with prior consent from the treating Physician. |
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