| EX1508 MICROSATELLITE INSTABILITY (MSI) PCR |
| Specimen: |
Submit formalin-fixed paraffin-embedded (FFPE) tissue block. Ship at room temperature. Block should have at least 10% tumor tissue. |
| Stability: |
| Room |
Refrigerated |
Frozen |
| NA |
NA |
NA |
|
| Method: |
PCR, Fragment analysis |
| Comment: |
Samples received on holidays will be reported in the next schedule/next working day. |
| Report: |
Contact us to know the TAT. |
| Usage: |
The presence of MSI is a sign of DNA mismatch repair deficiency that can be inherited, caused by a germline mutation in the MSH2 gene, or sporadic due to hypermethylation of the MLH1 promoter. Microsatellite instability (MSI)-High indicates a tumor with instability in 30% microsatellite markers. MSI-High occurs in approximately 90% of colorectal cancers from individuals with Lynch syndrome. |
| Doctor Specialty: |
Oncologist |
| Disease: |
Cancer |
| Components: |
ABI-16, ABI-17, ABI-19, ABI-20B, ABI-20A, BAT-25, BAT-26, BAT-40, CAT-25, NR-21, NR-22, NR-24, NR-27 |
| Courier Charges: |
|
| Home Collection: |
Available (*T&C Apply) |
| Department: |
MOLECULAR DIAGNOSTICS |
| Pre Test Information: |
Block should have at least 10% tumor tissue. |
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