| EX1492 METANEPHRINES FRACTIONATED, 24 HOUR URINE |
| Specimen: |
50 mL (10 mL min.) aliquot of 24-hour urine. Collect urine with an appropriate volume of 50% HCl to maintain pH between 1–and 2. Do not use concentrated HCl. Record 24-hour volume on the test request form and urine container. Ship refrigerated or frozen. |
| Stability: |
| Room |
Refrigerated |
Frozen |
| 8 hrs |
5 days |
30 days |
|
| Method: |
HPLC-EC |
| Comment: |
Initial testing for Pheochromocytoma should always include measurement of Plasma free or Urinary fractionated metanephrines. The recommended method for measurement is LC-MS/MS or HPLC-EC. Also, see PHEOCHROMOCYTOMA PROFILE. |
| Report: |
Contact us to know the TAT. |
| Usage: |
This assay is useful as a screening test for the presumptive diagnosis of catecholamine secreting Pheochromocytoma & Paragangliomas. Metanephrine and Normetanephrine are 3-Methoxy metabolites of Epinephrine and Normetanephrine respectively. These are further metabolized to VMA. This assay may be used as a first-order screening test. |
| Doctor Specialty: |
Oncologist |
| Disease: |
Cancer |
| Components: |
*Metanephrine *Normetanephrine |
| Courier Charges: |
0.00 |
| Home Collection: |
Available (*T&C Apply) |
| Department: |
HPLC |
| Pre Test Information: |
The patient should strictly avoid Alpha- Methyldopa, Buspirone, Codeine, Isoproterenol metabolite, Mandelamine, L-dopa, Paracetamol, Metoclopramide, pepper, alcoholic beverages, tea/coffee, tobacco, and strenuous exercise at least 72 hours before and during specimen collection. |
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