| EX1382 KRAS & NRAS MUTATION ANALYSIS PANEL |
| Specimen: |
Submit formalin-fixed paraffin-embedded tissue block. Ship at room temperature. Block should have at least 10% tumor tissue. |
| Stability: |
| Room |
Refrigerated |
Frozen |
| NA |
NA |
NA |
|
| Method: |
PCR, Fragment analysis, and Sequencing |
| Comment: |
Samples received on holidays will be reported in the next schedule/next working day. |
| Report: |
Contact us to know the TAT. |
| Usage: |
RAS mutations are commonly found in cancer tissue, causing a permanent activation of the signal transduction pathway downstream of the EGF receptor (EGFR), thus positive signaling for cell growth. Most frequent are KRAS mutations in codons 12,13 in the second (first transcribed) exon. Up to 45% of all colorectal cancer patients exhibit KRAS 12,13 mutations, while another 10-15% may have mutations in KRAS exons 3 and 4 or in the respective regions of the homologous NRAS gene. |
| Doctor Specialty: |
Oncologist |
| Disease: |
Cancer |
| Components: |
|
| Courier Charges: |
0.00 |
| Home Collection: |
Available (*T&C Apply) |
| Department: |
MOLECULAR DIAGNOSTICS |
| Pre Test Information: |
A duly filled NGS Test Requisition Form is mandatory. |
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