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Laboratory

Exult Diagnostics, Dr. Lal PathLabs

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IMMUNOPHENOTYPING BY FLOW CYTOMETRY: DOUBLE NEGATIVE T CELLS (DNT)

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EX1303      IMMUNOPHENOTYPING BY FLOW CYTOMETRY: DOUBLE NEGATIVE T CELLS (DNT)
Specimen: 3 mL (2 mL min.) whole blood in 1 Lavender Top (EDTA) tube AND 3 mL (2 mL min.) whole blood in 1 Green Top (Sodium Heparin) tube. Ship immediately at 18–22°C. DO NOT REFRIGERATE OR FREEZE. Specify time, date, and clinical details on the test request form.
Stability:
Room Refrigerated Frozen
24 hrs NA NA
Method: Flow Cytometry
Comment:
Report: Contact us to know the TAT.
Usage: Double negative T cells (DNT cells) are a consistent finding in Autoimmune lymphoproliferative syndrome (ALPS). Patients with ALPS show an increase in a normally rare population of T cells that are TCRab positive but negative for both CD4 and CD8 co-receptors. It is not a confirmatory diagnostic test. Abnormal results should be confirmed by correlating clinical history along with genetic testing for the relevant gene mutations.
Doctor Specialty: Pediatrician
Disease: Autoimmune Disorders
Components:
Courier Charges:
Home Collection: Available (*T&C Apply)
Department: FLOW CYTOMETRY
Pre Test Information: Give brief clinical history.