| EX1223 IMMUNOHISTOCHEMISTRY: P16 |
| Specimen: |
Submit Tissue in 10% formal-saline OR formalin-fixed paraffin-embedded Tissue Block. Ship at room temperature. |
| Stability: |
| Room |
Refrigerated |
Frozen |
| NA |
NA |
NA |
|
| Method: |
IHC |
| Comment: |
Samples received on holidays will be reported in the next schedule / next working day. |
| Report: |
Contact us to know the TAT. |
| Usage: |
p16 expression plays a major role in the evaluation of Cervical Squamous Intraepithelial lesions (SIL) & distinguishing dysplasia from benign mimics. Overexpression is seen in most high-risk HPV-associated squamous lesions whereas absent/focal weak expression is seen in normal/inflamed/atrophic cervical epithelium. p16 expression has also been seen in non-HPV-related tumors like High-grade serous carcinoma & Atypical uterine smooth muscle tumors like Leiomyosarcomas. Testing of oropharyngeal squamous cell carcinomas with p16 is also indicated where it serves as an excellent surrogate marker for active HPV. |
| Doctor Specialty: |
Oncologist |
| Disease: |
Cancer |
| Components: |
|
| Courier Charges: |
|
| Home Collection: |
Available (*T&C Apply) |
| Department: |
Histopathology |
| Pre Test Information: |
Provide a copy of the Histopathology report, Site of biopsy, and Clinical history. |
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