| EX1203 IMMUNOHISTOCHEMISTRY: LMO2 |
| Specimen: |
Submit Tissue in 10% formal-saline OR formalin-fixed paraffin-embedded Tissue Block. Ship at room temperature. |
| Stability: |
| Room |
Refrigerated |
Frozen |
| NA |
NA |
NA |
|
| Method: |
IHC |
| Comment: |
Samples received on holidays will be reported in the next schedule / next working day. |
| Report: |
Contact us to know the TAT. |
| Usage: |
LMO2 is a transcription factor that regulates vascular and hematopoietic systems and is involved in hematolymphoid neoplasia. LMO2 is preferentially expressed by germinal center B cells and may also be expressed in erythroid and myeloid precursors and in megakaryocytes. The expression has been observed in cases of Lymphoblastic leukemia and Acute myeloid leukemia. It is rarely expressed in mature T, natural killer, and plasma cell neoplasms and is absent from non-hematolymphoid tissues except for endothelial cells. In the diagnosis of B-cell lymphomas, LMO2 can be useful in an immunohistochemical panel to assign a germinal center phenotype thereby helping in the classification of lymphomas. LMO2 is used to differentiate Follicular lymphoma (LMO2 positive) from nodal Marginal zone lymphoma (LMO2 negative). |
| Doctor Specialty: |
Oncologist |
| Disease: |
Cancer |
| Components: |
|
| Courier Charges: |
|
| Home Collection: |
Available (*T&C Apply)
|
| Department: |
Histopathology |
| Pre Test Information: |
Provide a copy of the Histopathology report, Site of biopsy, and Clinical history. |
Reviews
There are no reviews yet.