| EX1115 IMMUNOHISTOCHEMISTRY: CALDESMON |
| Specimen: |
Submit Tissue in 10% formal-saline OR formalin-fixed paraffin-embedded Tissue Block. Ship at room temperature. |
| Stability: |
| Room |
Refrigerated |
Frozen |
| NA |
NA |
NA |
|
| Method: |
IHC |
| Comment: |
Samples received on holidays will be reported in the next schedule / next working day. |
| Report: |
Contact us to know the TAT. |
| Usage: |
Caldesmon is a smooth muscle and non-muscle regulatory protein that interacts with actin, myosin, tropomyosin, and calmodulin. Smooth muscle caldesmon is an elongated molecule with a calmodulin, tropomyosin, and actin-binding region at the C-terminus and a myosin-binding domain at the N-terminus. Caldesmon stimulates the actin-binding of tropomyosin which increases the stabilization of actin filament structure. In muscle tissues, caldesmon inhibits the actomyosin ATPase by binding to F-Actin. Caldesmon is a useful marker for smooth muscle tumors. |
| Doctor Specialty: |
Oncologist, Pathologist |
| Disease: |
Cancer |
| Components: |
|
| Courier Charges: |
0.00 |
| Home Collection: |
Available (*T&C Apply) |
| Department: |
Immunohistochemistry |
| Pre Test Information: |
Provide a copy of the Histopathology report, Site of biopsy, and Clinical history. |
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