| EX0687 FISH: MULTIPLE MYELOMA EXTENDED PANEL WITH POSITIVE SELECTION OF CD138 CELLS: HYPODIPLOIDY/HYPERDIPLOIDY |
| Specimen: |
8 ml (6 ml min.) Whole blood from 2 Green Top (Sodium Heparin) tubes OR 4 ml (2 ml min.). Bone marrow from Green Top (Sodium Heparin) tube. Ship at 18-22°C. DO NOT FREEZE. |
| Stability: |
| Room |
Refrigerated |
Frozen |
| 48 hrs |
NA |
NA |
|
| Method: |
FISH |
| Comment: |
FISH is performed after positive selection of CD138 cells thereby providing more accurate results. Samples received on holidays will be reported in the next schedule / next working day. |
| Price: |
21900.00 |
| Report: |
Contact us to know the TAT. |
| Usage: |
Multiple myeloma (MM) is a plasma cell malignancy characterized by complex and heterogeneous cytogenetic abnormalities. Multiple myeloma is divided into hyperdiploid multiple myeloma (HMM) and non-hyperdiploid multiple myeloma (NHMM). Approximately 55–60% of patients have the hyperdiploid karyotype, with trisomies of eight specific chromosomes, including chromosomes 3, 5, 7, 9, 11, 15, 19, and 21. The remaining cases form the non-hyperdiploid group, frequently involving translocations and hemizygous deletion of chromosome 13. The two MM subtypes have different prognoses and survival outcomes. The HMM patients tend to have a better prognosis than NHMM patients. Therefore, cytogenetic and genomics-based prognosis models should use the subtype status as a covariate to help uncover novel and independent factors for prognosis and drug response. |
| Doctor Specialty: |
Hematologist, Oncologist |
| Disease: |
Cancer |
| Components: |
*1q21 gain/loss *13q14.3 deletion *17p deletion *t(11;14)(q13;q32) *t(4;16)(p16;q32) *t(14;16)(q32;q23) *t(14;20)(q32;q12) *CEN3 *CEN5 *CEN7 *CEN9 *CEN11 *CEN21 |
| Courier Charges: |
|
| Home Collection: |
Available (*T&C Apply) |
| Department: |
CYTOGENETICS |
| Pre Test Information: |
A duly filled chromosome and FISH analysis Requisition form is mandatory. |
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