| EX0681 FISH: MDS PANEL CHROMOSOMES 5q, 7q, 8q & 20q |
| Specimen: |
5 mL (3 mL min.) Whole blood OR 4 mL ( 2 mL min.) Bone Marrow from 2 Green Top (Sodium Heparin) tubes. Ship at 18-22°C. DO NOT FREEZE. |
| Stability: |
| Room |
Refrigerated |
Frozen |
| 48 hrs |
NA |
NA |
|
| Method: |
FISH |
| Comment: |
Samples received on holidays will be reported in the next schedule / next working day. |
| Report: |
Contact us to know the TAT. |
| Usage: |
Myelodysplastic syndrome (MDS) describes a group of clonal hematopoietic disorders resulting in ineffective production of one or more of the myeloid cell lineages which increases the risk by 35-40% for transformation to Acute Myeloid Leukemia (AML). More than 50% of patients with MDS have clonal cytogenetic abnormalities and these can be classified into 3 risk groups. Good prognosis: Deletion in the long arm of chromosomes 5 & 20 is seen in 30% of cases & prognosis is favorable; Intermediate risk: Trisomy 8 is associated with a mean survival of 23 to 26 months; Poor risk: Monosomy 7 & complex chromosomal abnormalities are associated with a median survival of <1 year. |
| Doctor Specialty: |
Oncologist, Hematologist |
| Disease: |
Cancer |
| Components: |
*del 5q31.2 *7q22.1 *7q36.1 *20q11 *trisomy 8 |
| Courier Charges: |
0.00 |
| Home Collection: |
Available (*T&C Apply) |
| Department: |
CYTOGENETICS |
| Pre Test Information: |
A duly filled Chromosome & FISH analysis Requisition Form is mandatory. |
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