| EX0678 FISH: HER2 (ERBB2) AMPLIFICATION |
| Specimen: |
Submit Formalin fixed paraffin embedded Tissue Block. Ship at room temperature. The tissue block must contain 10% tumor tissue. |
| Stability: |
| Room |
Refrigerated |
Frozen |
| NA |
NA |
NA |
|
| Method: |
FISH |
| Comment: |
Samples received on holidays will be reported in the next schedule / next working day. |
| Report: |
Contact us to know the TAT. |
| Usage: |
Amplification or overexpression of the human epidermal growth factor receptor 2 genes (ERBB2) is seen in 15-20% of patients with breast cancer and is associated with shortened disease-free & overall survival. Since targeted therapies are available to effectively treat Her2 positive breast cancer, accurate assessment of Her2 status is critically important in the selection of correct therapy such as Trastuzumab (Herceptin) / Pertuzumab. The FISH technique is especially useful in Her2 equivocal tumors. As per ASCO 2018 guidelines, all newly diagnosed patients with breast cancer who develop metastatic disease should undergo a Her2 test on tissue from the metastatic site. |
| Doctor Specialty: |
Oncologist |
| Disease: |
Cancer |
| Components: |
|
| Courier Charges: |
0.00 |
| Home Collection: |
Available (*T&C Apply) |
| Department: |
CYTOGENETICS |
| Pre Test Information: |
A duly filled Chromosome & FISH analysis Requisition Form is mandatory. |
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