| EX0660 FISH: 17p (TP53) DELETION |
| Specimen: |
5 mL (3 mL min.) Whole blood OR 4 mL ( 2 mL min.) Bone Marrow from 2 Green Top (Sodium Heparin) tubes. Ship at 18-22°C. DO NOT FREEZE. |
| Stability: |
| Room |
Refrigerated |
Frozen |
| 48 hrs |
NA |
NA |
|
| Method: |
FISH |
| Comment: |
Samples received on holidays will be reported in the next schedule / next working day. |
| Report: |
Contact us to know the TAT. |
| Usage: |
Mutations in the TP53 gene are associated with the deletion of chromosome 17. This is indicative of poor prognosis in Multiple Myeloma (MM) cases. Early cases of MM may not show this deletion but as the disease advances, 17p deletion can be detected. Screening for 17p deletion in MM cases aids management decisions & directs these high-risk patients towards alternative therapies. This deletion has also been detected in Chronic Lymphocytic Leukemia (CLL) & is associated with a poor prognosis. |
| Doctor Specialty: |
Oncologist |
| Disease: |
Multiple Myeloma |
| Components: |
|
| Courier Charges: |
0.00 |
| Home Collection: |
Available (*T&C Apply) |
| Department: |
CYTOGENETICS |
| Pre Test Information: |
A duly filled Chromosome & FISH analysis Requisition Form is mandatory. |
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