| EX0657 FIRST TRIMESTER TRIPLE MARKER |
| Specimen: |
3 ml (1.5 ml min.) serum from 1 SST. Ship refrigerated or frozen. The test is valid between 10-13 weeks gestation. Provide maternal Date of birth (dd/mm/yy); Height, weight, IVF, Smoking, History of blood pressure, Diabetes and Preeclampsia in a previous pregnancy, Previous h/o trisomy birth, Two readings of Blood pressure measurement for each arm; USG report between 11-13 weeks gestation including CRL, NT & Nasal Bone, number of fetuses, Uterine artery PI in Maternal Serum Screen Form & Preeclampsia Screening Form. |
| Stability: |
| Room |
Refrigerated |
Frozen |
| NA |
8 hrs |
12 weeks |
|
| Method: |
ECLIA |
| Comment: |
The test is done on FMF accredited (Roche) platform. The International Federation of Gynecology and Obstetrics (FIGO, 2019) recommends All pregnant women should be screened for preterm PE during early pregnancy by the first-trimester combined test with maternal risk factors and biomarkers as a one-step procedure. |
| Report: |
Contact us to know the TAT. |
| Usage: |
Preeclampsia (PE) appears to be due to the release of angiogenic factors from the placenta that induces endothelial dysfunction. Serum levels of PlGF (placental growth factor) are altered in women with PE and can discriminate normal pregnancy from PE even before clinical symptoms occur. In normal pregnancy, the pro-angiogenic factor PlGF increases during the first two trimesters and then decreases as pregnancy progresses to term. In PE, PlGF levels have been found to be lower than in normal pregnancy. |
| Doctor Specialty: |
Gynecologist |
| Disease: |
Pre-eclampsia |
| Components: |
*Free Beta HCG *Pregnancy Associated Plasma Protein A (PAPP-A) *Placental Growth Factor (PlGF) *Risk Assessment for early and late-onset Pre-eclampsia *Risk Assessment for Trisomy 13, 18 & 21 |
| Courier Charges: |
|
| Home Collection: |
Available (*T&C Apply) |
| Department: |
IMMUNOASSAY |
| Pre Test Information: |
The test is valid between 10-13 weeks gestation. Provide details in the Maternal Serum Screen requisition form & Preeclampsia screening form. |
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