| EX0646 FIB-4 INDEX |
| Specimen: |
3 mL (2 mL min.) whole blood from 1 Lavender Top (EDTA) tube AND 2 mL (1 mL min.) serum from 1 SST. Ship refrigerated. DO NOT FREEZE. |
| Stability: |
| Room |
Refrigerated |
Frozen |
| 2 hrs |
48 hrs |
NA |
|
| Method: |
IFCC, Electrical Impedance |
| Comment: |
Also, see ENHANCED LIVER FIBROSIS (ELF) Panel. |
| Report: |
Contact us to know the TAT. |
| Usage: |
FIB-4 index is a mathematical calculation that incorporates routine clinical and laboratory parameters like Age, AST, ALT, and Platelet count into a single score. It is a useful marker of liver fibrosis with a sensitivity and specificity of 64% and 68% respectively for significant fibrosis. For cirrhosis, the sensitivity and specificity are 90% and 58% respectively. Liver biopsy is considered the gold standard for assessing liver fibrosis in Chronic Hepatitis patients. However, being an invasive procedure, it has some limitations. FIB-4 on the other hand offers a simple, inexpensive, and non-invasive alternative to assess liver fibrosis. This index takes into consideration the fact that elevation of AST more than ALT is related to mitochondrial injury associated with advanced fibrosis and thrombocytopenia is associated with progression of fibrosis. |
| Doctor Specialty: |
Gastroenterologist |
| Disease: |
Diseases of Liver |
| Components: |
*AST (SGOT) *ALT (SGPT) *Platelet count |
| Courier Charges: |
|
| Home Collection: |
Available (*T&C Apply) |
| Department: |
Biochemistry |
| Pre Test Information: |
No special preparation required |
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