Additional information
Laboratory | Exult Diagnostics, Dr. Lal PathLabs, Metropolis Labs |
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Laboratory | Exult Diagnostics, Dr. Lal PathLabs, Metropolis Labs |
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₹ 9900 – ₹ 10500
EX0564 DIABETES TYPE 1 AUTOIMMUNE PROFILE | |||||||
Specimen: | 5 mL (3 mL min.) serum from 1 SST. Ship refrigerated or frozen. | ||||||
Stability: |
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Method: | Enzyme Immunoassay, IFA | ||||||
Comment: | |||||||
Report: | Contact us to know the TAT. | ||||||
Usage: | Type 1 Diabetes mellitus (Insulin-dependent diabetes mellitus, IDDM) is the result of a T-cell mediated destruction of the beta cells in genetically predisposed individuals. Autoantibodies to a variety of islet cell antigens appear during the course of autoimmune insulitis. Type 1 diabetes is characterized by the presence of distinct circulating autoantibodies including autoantibodies to glutamic acid decarboxylase (GAD), protein tyrosine phosphatase (IA2), insulin, and autoantibodies directed against cytoplasmic components of islet cells. Measurement of autoantibodies to GAD (GADA), IA2 (IA2A), insulin (IAA), and cytoplasmic islet cell antigens (ICA) has been shown to be of significant value for the diagnosis and prediction of type 1 diabetes in first-degree relatives of diabetic patients. One or several of these autoantibodies are found in most new-onset type 1 diabetic patients. They can also be detected before the onset of the disease and characterize the so-called prediabetic period. These autoantibodies help to estimate the risk of an individual developing type 1 diabetes. Testing for all autoantibodies (GADA, IA2A, IAA, ICA) is highly recommended for risk assessment of type 1 diabetes. | ||||||
Doctor Specialty: | Diabetologist, Physician | ||||||
Disease: | Diabetes | ||||||
Components: | *GAD-65 *Anti-IA2 *Insulin Autoantibody *Islet Cell Antibody | ||||||
Courier Charges: | 0.00 | ||||||
Home Collection: | Available (*T&C Apply) | ||||||
Department: | Immunology | ||||||
Pre Test Information: | No special preparation required |
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