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Laboratory

Exult Diagnostics, Dr. Lal PathLabs, Metropolis Labs, Oncquest Labs, Pathkind Labs

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DES-GAMMA CARBOXY PROTHROMBIN (DCP)/PIVKA II, SERUM

 3100 4900

EX0552      DES-GAMMA CARBOXY PROTHROMBIN (DCP)/PIVKA II, SERUM
Specimen: 2 mL (0.5 mL min.) serum from 1 SST. Ship refrigerated or frozen. Give brief clinical history.
Stability:
Room Refrigerated Frozen
8 hrs 1 week 6 weeks
Method: Chemiluminescent Microparticle Immunoassay
Comment: It is recommended to measure two or more different tumor markers (AFP & DCP) for the diagnosis of HCC at an early stage. Samples received on holidays will be reported in the next schedule/next working day.
Report: Contact us to know the TAT.
Usage: Des-gamma carboxyprothrombin (DCP) also known as PIVKA II (Prothrombin induced by Vitamin K antagonist II) is abnormal prothrombin that is increased in the sera of patients with Hepatocellular Carcinoma (HCC). Unlike AFP, it is not elevated in Chronic Liver Disease, Cirrhosis, pregnancy, or Germ Cell Tumors. It is a complementary biomarker to AFP in HCC and increases the sensitivity (83%) and specificity (84%) for HCC when used in combination. It is recommended to measure two or more different tumor markers (AFP, DCP, or AFP L3) for the diagnosis of HCC at an early stage. Moreover, DCP has been found to correlate better with tumor size, histological grade, portal vein invasion, and/or intrahepatic metastasis in patients with HCC.
Doctor Specialty: Oncologist, Gastroenterologist
Disease: Cancer
Components:
Courier Charges:
Home Collection: Available (*T&C Apply)
Department: Immunology
Pre Test Information: Give brief clinical history.