| EX0360 CHRONIC LYMPHOCYTIC LEUKEMIA (CLL), PROGNOSTIC PANEL |
| Specimen: |
4 mL (2 mL min.) whole blood from 1 Lavender top (EDTA) tube AND 5 mL (3 mL min.) whole blood OR 4 mL ( 2 mL min.) Bone Marrow from 2 Green Top (Sodium Heparin) tubes. Ship at 18-22°C. DO NOT FREEZE. |
| Stability: |
| Room |
Refrigerated |
Frozen |
| 24 hrs |
NA |
NA |
|
| Method: |
PCR Sequencing, FISH, Flow cytometry |
| Comment: |
|
| Report: |
Contact us to know the TAT. |
| Usage: |
Chronic Lymphocytic Leukemia (CLL) results in the progressive accumulation of CD5(+) CD23(+) B lymphocytes that appear morphologically mature but are functionally incompetent in bone marrow, blood, spleen, and lymph nodes of the affected person. Chromosomal translocations are rare events in B-CLL, whereas copy number changes of certain chromosomal regions are frequent, and some of these have been found to be highly prognostic markers of CLL. More than 2% mutation in the IgVH Gene is a favorable prognostic marker. |
| Doctor Specialty: |
Hematologist, Oncologist |
| Disease: |
Leukemia |
| Components: |
*ZAP 70 *CD38 *CD49d *IGVH *del11q23(ATM) *del17p13.1(TP53) *del13q14.3 *del13q34 *Trisomy 12 |
| Courier Charges: |
|
| Home Collection: |
Available (*T&C Apply) |
| Department: |
MOLECULAR DIAGNOSTICS |
| Pre Test Information: |
A duly filled Chromosome & FISH analysis Requisition Form is mandatory. |
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