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Laboratory

Exult Diagnostics, Dr. Lal PathLabs

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CARCINOID TUMOR PANEL

 10000

EX0297      CARCINOID TUMOR PANEL
Specimen: 3 mL (2 mL min.) serum from 1 SST AND 2 mL (1 mL min.) plasma from 1 Lavender Top (EDTA) tube AND 50 mL (10 mL min.) aliquot of 24-hour urine. Collect urine with an appropriate volume of 50% HCl to maintain pH between 1–2. Do not use concentrated HCl. Record 24-hour volume on the test request form and urine container. Ship frozen. DO NOT THAW.
Stability:
Room Refrigerated Frozen
NA NA 2 WEEKS
Method: HPLC-EC, TRACE
Comment: To achieve maximum sensitivity in the initial diagnosis of suspected Carcinoid tumors, it is important to measure serum Serotonin, Urinary 5-HIAA & serum Chromogranin A.
Report: Contact us to know the TAT.
Usage: Carcinoids are neuroectodermal tumors of the gastrointestinal tract and pancreas. Carcinoid tumors are traditionally classified into foregut Carcinoids, midgut Carcinoids, and hindgut Carcinoids. The clinical manifestation of Carcinoid tumors is extremely varied and often obscure. These variable presentations often lead to delay incorrect diagnoses. Midgut Carcinoids release a large quantity of Serotonin (5-Hydroxytryptamin; 5-HT) into circulation. However, tumors derived from the foregut primarily secrete 5-Hydroxytryptophan (5-HTP) and Histamin. Primary hindgut Carcinoids show no 5-HT or 5-HTP secretory activity. In contrast, Chromogranin A levels are elevated in almost all hindgut tumors.
Doctor Specialty: Endocrinologist
Disease: Disorders of Endocrine System
Components: *5-HIAA (5-Hydroxy Indole Acetic Acid), 24 Hour Urine *Chromogranin A *Serotonin (5-HT), Serum
Courier Charges:
Home Collection: Available (*T&C Apply)
Department: Biochemistry
Pre Test Information: Proton pump inhibitor medications should be discontinued for at least 2 weeks prior to sample collection. The patient should strictly avoid banana, kiwi, walnut, avocado, brinjal, pineapple, plum, tomato & drugs like Fluorouracil, Melphalan, Paracetamol & Acetaminophen, Heparin, L-dopa, Reserpine, Salicylates, Chlorpromazine, Imipramine, Isoniazid, MAO inhibitors, Phenothiazines, Promethazine, alcoholic beverages, caffeine, tea/coffee, tobacco and strenuous exercise at least 72 hrs before and during specimen collection.