| EX0235 BRCA1 & BRCA2 MUTATION ADVANCED PANEL |
| Specimen: |
4 mL (2 mL min.) whole blood in 1 Lavender top (EDTA) tube. Ship refrigerated. DO NOT FREEZE. |
| Stability: |
| Room |
Refrigerated |
Frozen |
| 6 hrs |
1 week |
NA |
|
| Method: |
Next-Generation Sequencing |
| Comment: |
Genetic counseling will be provided with prior appointments. MLPA is done for confirmation if large indels are detected. |
| Report: |
Contact us to know the TAT. |
| Usage: |
The presence of single germline SNPs like BRCA1 & BRCA2 genes increases the relative & absolute risk of developing breast cancer & other cancers. Women with this inherited mutated gene allele have a 60-80% chance of developing breast cancer & a 33% chance of developing ovarian cancer. Breast cancer developing in BRCA1 mutated patients is usually “Triple Negative” whereas BRCA2 mutated patients are usually ER-positive. This assay detects most of the mutations and insertions/deletions in the BRCA gene which is linked to breast cancer. This assay is useful for screening family members of known Breast cancer patients for predisposition. |
| Doctor Specialty: |
Oncologist |
| Disease: |
Cancer |
| Components: |
*BRCA1 *BRCA2 |
| Courier Charges: |
|
| Home Collection: |
Available (*T&C Apply) |
| Department: |
MOLECULAR DIAGNOSTICS |
| Pre Test Information: |
A duly filled BRCA 1 & 2 informed consent form for genetic testing is mandatory. |
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