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| Laboratory | Exult Diagnostics, Dr. Lal PathLabs |
|---|
₹ 10000
| EX0173 AUTOGEN PLUS PANEL | |||||||
| Specimen: | 5 mL (3 mL min.) Whole blood in 2 Green Top (Sodium Heparin) tubes each of Husband & Wife. Ship refrigerated. DO NOT FREEZE. The specimen must reach Lab within 24 hrs. Duly filled Chromosome and FISH analysis Requisition forms are mandatory AND 3 mL Whole blood in 1 Blue Top (Sodium Citrate) tube. Mix thoroughly by inversion. Transport to Lab within 4 hours. If this is not possible, make PPP within 1 hour of collection as follows: Centrifuge sample at 3600 rpm for 15 min. & transfer supernatant to a clean plastic tube. Centrifuge this supernatant again at 3600 rpm for 15 min. & finally, transfer the supernatant (PPP) to 1 labeled clean plastic screw-capped vial. FREEZE IMMEDIATELY. Ship frozen. DO NOT THAW. Overnight fasting is preferred. Duly filled Coagulation Requisition Form is mandatory AND 4 mL (3 mL min.) Serum from 2 SST’s. Ship refrigerated or frozen. | ||||||
| Stability: |
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| Method: | Culture, Robotic Microscopy, Karyotype, Enzyme Immunoassay, Electromechanical Clot Detection | ||||||
| Comment: | It is recommended that the patient discontinues Heparin for 1 day and Oral Anticoagulants for 7 days prior to sampling as these drugs may affect test results. Discontinuation should be with prior consent from the treating Physician. | ||||||
| Report: | Contact us to know the TAT. | ||||||
| Usage: | Chromosome analysis helps in the diagnosis of a wide variety of congenital conditions. It helps in the identification of congenital chromosome abnormalities like Aneuploidy (Trisomy / Monosomy) & structural chromosome abnormalities. Testing for Phospholipid antibodies is indicated in cases of unexplained arterial/venous thrombosis, pregnancy with unexplained fetal deaths, spontaneous abortions, presence of unexplained cutaneous circulatory disturbance like Livido reticularis, and presence of Systemic rheumatic disease like LE. This test is also used in cases of unexplained thrombocytopenia, Hemolytic anemia & Non-bacterial thrombotic endocarditis. Lupus Anticoagulants are heterogenous IgG or IgM autoantibodies which interfere with phospholipid-dependent in vitro coagulation tests, particularly Activated Partial Thromboplastin Time (APTT). These antibodies are associated with thrombosis (arterial & venous), recurrent abortions, neurological & neuropsychiatric disorders. Cardiolipin antibodies are useful in identifying patients with an increased risk of thrombosis, recurrent spontaneous abortions, and phospholipid antibody syndrome. Cardiolipin antibodies may be elevated in patients with SLE and related autoimmune disorders. Anti Beta 2 Glycoprotein 1 (Beta 2GP1) antibodies are independent risk factors for thrombosis in autoimmune diseases and complications of pregnancy. The presence of these antibodies can also be helpful in the diagnosis of Antiphospholipid syndrome. | ||||||
| Doctor Specialty: | Gynecologist | ||||||
| Disease: | Infertility | ||||||
| Components: | *Chromosome Analysis (Karyotype), Blood *Lupus Anticoagulant Panel; LAC Panel *Cardiolipin Antibodies Panel IgA, IgG & IgM *Phospholipid Antibodies Panel IgG & IgM *Beta 2 Glycoprotein 1 Panel IgA, IgG & IgM | ||||||
| Courier Charges: | |||||||
| Home Collection: | Available (*T&C Apply) | ||||||
| Department: | Immunology | ||||||
| Pre Test Information: | Give brief clinical history. | ||||||
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