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Laboratory

Exult Diagnostics, Dr. Lal PathLabs

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AUTOGEN PANEL

 8500

EX0172      AUTOGEN PANEL
Specimen: 5 mL (3 mL min.) whole blood in 2 Green Top (Sodium Heparin) tubes each of Husband & Wife. Ship refrigerated immediately. DO NOT FREEZE. The specimen must reach Lab within 24 hours. Duly filled Chromosome and FISH Analysis Requisition Form is mandatory AND 3 mL whole blood in 1 Blue Top (Sodium Citrate) tube. Mix thoroughly by inversion. Transport to Lab within 4 hours. If this is not possible, make PPP within 1 hour of the collection as follows: Centrifuge sample at 3600 rpm for 15 min. & transfer supernatant to a clean plastic tube. Centrifuge this supernatant again at 3600 rpm for 15 mins. & finally, transfer the supernatant (PPP) to 1 labeled clean plastic screw-capped vial. FREEZE IMMEDIATELY. Ship frozen. DO NOT THAW. Overnight fasting is preferred. A duly filled Coagulation Requisition Form is mandatory. AND 4 mL (3 mL min.) serum from 2 SST’s. Ship refrigerated or frozen.
Stability:
Room Refrigerated Frozen
Ship at specified temperatures Ship at specified temperatures Ship at specified temperatures
Method: Culture, Robotic Microscopy, Karyotype; Electromechanical Clot Detection; Enzyme Immunoassay
Comment: It is recommended that the patient discontinues Heparin for 1 day and Oral Anticoagulants for 7 days prior to sampling as these drugs may affect test results. Discontinuation should be with prior consent from the treating Physician.
Report: Contact us to know the TAT.
Usage: Chromosome analysis helps in the diagnosis of a wide variety of congenital conditions. It helps in the identification of congenital chromosome abnormalities like Aneuploidy (Trisomy / Monosomy) & structural chromosome abnormalities. Lupus Anticoagulants are heterogenous IgG or IgM autoantibodies which interfere with phospholipid-dependent in vitro coagulation tests, particularly Activated Partial Thromboplastin Time (APTT). These antibodies are associated with thrombosis (arterial & venous), recurrent abortions, neurological & neuropsychiatric disorders. Cardiolipin antibodies are useful in identifying patients with an increased risk of thrombosis, recurrent spontaneous abortions, and phospholipid antibody syndrome. Testing for Phospholipid antibodies is indicated in cases of unexplained arterial/venous thrombosis, pregnancy with unexplained fetal deaths, spontaneous abortions, presence of unexplained cutaneous circulatory disturbance like Livido reticularis, and presence of Systemic rheumatic disease like LE. This test is also used in cases of unexplained thrombocytopenia, Hemolytic anemia & Non-bacterial thrombotic endocarditis.
Doctor Specialty: Gynecologist
Disease: Infertility
Components: *Chromosome Analysis (Karyotype), Blood *Lupus Anticoagulant Panel; LAC Panel *Cardiolipin Antibodies Panel IgA, IgG & IgM *Phospholipid Antibodies Panel IgG & IgM
Courier Charges:
Home Collection: Available
Department: Immunology
Pre Test Information: Overnight fasting is preferred. It is recommended that patient discontinues Heparin for 1 day and Oral Anticoagulants for 7 days prior to sampling as these drugs may affect test results. Discontinuation should be with prior consent from the treating Physician. Duly filled Chromosome and FISH Analysis Requisition Form and Coagulation Requisition Form is mandatory.