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Laboratory

Exult Diagnostics, Dr. Lal PathLabs

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ANEMIA OF CHRONIC DISEASE (ACD) PANEL

 2500

EX0111      ANEMIA OF CHRONIC DISEASE (ACD) PANEL
Specimen: 3 mL (1.5 mL min ) serum from 1 SST AND 3 mL (2 mL min.) whole blood in 1 Lavender Top (EDTA) tube. Ship refrigerated. DO NOT FREEZE.
Stability:
Room Refrigerated Frozen
6 hrs 48 hrs NA
Method: Spectrophotometry, Electrical Impedance, VCS, Nephelometry, Chemiluminescent Immunoassay, Immunoturbidimetry
Comment:
Report: Contact us to know the TAT.
Usage: Anemia of Chronic Disease (ACD) and Iron Deficiency Anemia (IDA) is the most prevalent form of anemia and often occurs concurrently. Patients with IDA and concurrent inflammation present a diagnostic dilemma. IDA and ACD are differentiated primarily by estimates of iron status such as ferritin, serum iron, total iron-binding capacity, and transferrin saturation. However, these tests are directly affected by chronic disease leading to equivocal results, hindering clinical interpretation. Ferritin levels are typically reduced in IDA but may be increased by acute-phase responses in ACD. Soluble transferrin receptor (sTfR) levels are not affected by inflammation and are typically elevated in IDA. Using all the three (ferritin, sTfR, and sTfR index) parameters in combination doubles the detection of IDA from 41% (ferritin alone) to 92%.
Doctor Specialty: Hematologist
Disease: Anemia
Components: *Serum Iron studies *CBC *Ferritin *sTfR *sTfR Index *CRP
Courier Charges:
Home Collection: Available (*T&C Apply)
Department: Biochemistry
Pre Test Information: Overnight fasting & sampling before 12 noon is preferred. Avoid iron supplements for a minimum of 24 hours prior to specimen collection.