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| Laboratory | Exult Diagnostics, Dr. Lal PathLabs |
|---|
₹ 25000
| EX0028 ACUTE LEUKEMIA DIAGNOSTIC COMPREHENSIVE PROFILE | |||||||
| Specimen: | 5 mL (3 mL min.) whole blood in 2 Lavender Top (EDTA) tubes AND 2 peripheral blood smears AND 4 mL (2.5 mL min.) Bone marrow Aspirate in 2 Green Top (Sodium heparin) tubes AND 4 Bone marrow aspirate smears, air dried & fixed in 100% methanol for 30 minutes. Ship at 18-22°C. DO NOT FREEZE. A duly filled Chromosome and FISH analysis Requisition form (Form 17) is mandatory. | ||||||
| Stability: |
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| Method: | Electrical Impedance, VCS, Microscopy, Flow cytometry, FISH, Karyotyping, PCR Fragment Analysis | ||||||
| Comment: | Samples received on holidays will be reported in the next schedule/next working day. Special stains include Prussian Blue Reaction for Iron. | ||||||
| Report: | Contact us to know the TAT. | ||||||
| Usage: | Acute leukemia is broadly classified into Acute myeloid leukemia (AML), Acute lymphoblastic leukemia (ALL), and Acute leukemias of ambiguous lineage (mixed phenotype Acute leukemia and Acute undifferentiated leukemia). This comprehensive panel is on a par with the 2016 Revision to the WHO classification of Acute leukemia which incorporates morphology, immunophenotype, cytogenetics, and molecular study. The morphological evaluation of the blood and bone marrow is followed by flow cytometry with an extended Acute leukemia panel for lineage determination and karyotyping, PCR / FISH for characterization of recurrent genetic abnormalities for a comprehensive diagnosis, personalized/targeted therapy, and monitoring. | ||||||
| Doctor Specialty: | Hematologist | ||||||
| Disease: | Cancer | ||||||
| Components: | *CBC *Peripheral blood smear *Bone Marrow Examination Panel 1 *Leukemia diagnostic panel : Acute leukemia – T, B or Myeloid *Cytogenetic / Molecular genetic studies for : AML FISH – t(8;21)(q22;q22.1);RUNX1-RUNX1T1; t(15;17); PML-RARA;inv(16)(p13.1q22)/ t(16;16)(p13.1;q22);CBFB-MYH11; t(9;11)(p21.3;q23.3);MLLT3-KMT2A; PCR – FLT3 & NPM1 gene mutation. ALL FISH – t(12;21)(p13.2;q22.1); ETV6-RUNX1; t(9;22)(q34.1;q11.2);BCR-ABL1; t(1;19)(q23;p13.3);TCF3-PBX1; Karyotyping for hyper/hypo diploidy. MPAL FISH – t(9;22)(q34.1;q11.2);BCR-ABL1 | ||||||
| Courier Charges: | |||||||
| Home Collection: | Available (*T&C Apply) | ||||||
| Department: | CYTOGENETICS | ||||||
| Pre Test Information: | A duly filled Chromosome and FISH analysis Requisition form is mandatory. | ||||||
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