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Laboratory

Exult Diagnostics, Dr. Lal PathLabs

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5 FLUOROURACIL (5FU) TOXICITY

 7000

EX0011      5 FLUOROURACIL (5FU) TOXICITY
Specimen: 4 mL (2 mL min.) whole blood from 1 Lavender Top (EDTA) tube. Ship refrigerated. DO NOT FREEZE. A duly filled Genomics clinical Information Requisition Form (Form 20) is mandatory.
Stability:
Room Refrigerated Frozen
6 hrs 1 week NA
Method: PCR, Sequencing
Comment: Samples received on holidays will be reported in the next schedule/next working day.
Report: Contact us to know the TAT.
Usage: 5-Fluorouracil (5-FU) is a commonly used anticancer drug. It functions by irreversibly inhibiting thymidylate synthase. 5-FU is widely used in a number of cancers worldwide. Detoxification of 5-FU is mediated by the dihydropyrimidine dehydrogenase (DPD) gene. Apart from 5-FU, the gene also is involved in the detoxification of Capecitabine, and Tegafur. Genetic variations in the gene can cause a partial or complete deficiency of function, which may lead to severe drug toxicity.
Doctor Specialty: Oncologist
Disease: Pharmacogenomics
Components:
Courier Charges:
Home Collection: Available (*T&C Apply)
Department: MOLECULAR DIAGNOSTICS
Pre Test Information: A duly filled Genomics clinical Information Requisition Form is mandatory.