Amniotic Band Syndrome Overview
Amniotic band syndrome is a well-known condition potentially associated with a variety of different birth defects. The abnormalities occur after the affected parts of the body have formed normally in early development. The severity of amniotic band syndrome can range from a single, isolated finding to multiple, disfiguring complications. The arms and legs are most often affected. The head and face and, in some patients, various internal organs can also be affected. The exact cause of amniotic band syndrome is unknown and controversial.
Two main theories have been proposed to explain the development of the disorder. One theory attributes the disorder to causes that arise internally within the fetus (intrinsic theory); the other theory attributes the disorder to causes acting upon the fetus externally (extrinsic theory). It is likely that both internal and external factors can cause the amniotic band syndrome, and that the cause of the disorder in one infant may be different from the cause in another infant.
Symptoms
- Creases, or indentations, around their finger, hand, arm, toe, foot or leg
- All or part of a limb missing
- Swelling (edema) because bands restrict the flow of blood or lymph
- A difference in the length of their arms or legs
- A gap (cleft) or other difference in their head, face, belly or chest
When to see a Doctor
It is typically very difficult to detect amniotic band syndrome before birth, but the condition can sometimes be detected via ultrasound. Many times amniotic band syndrome is diagnosed after delivery during a physical examination of the newborn.