Multiple Endocrine Neoplasia Type 1 Overview
Multiple endocrine neoplasia, type 1 (MEN 1), sometimes called Wermer’s syndrome, is a rare disorder that causes tumors in the endocrine glands and parts of the small intestine and stomach. In MEN 1, the endocrine glands — usually the parathyroids, pancreas and pituitary — grow tumors and release excessive amounts of hormones that can lead to disease. However, the tumors are usually noncancerous (benign).
The excess hormones can cause a wide variety of signs and symptoms. These can include tiredness, bone pain, broken bones, kidney stones, and ulcers in the stomach or intestines. MEN 1 can’t be cured. But regular testing can detect problems, and doctors can provide treatment as needed. MEN 1 is an inherited disorder. This means people who have the gene mutation can pass it on to their children. Each child has a 50% chance of inheriting the disorder.
Symptoms
- Tiredness
- Bone pain
- Broken bones
- Kidney stones
- Ulcers in the stomach or intestines
![](https://exultdiagnostics.com/wp-content/uploads/2021/09/MEN-2-1024x926.jpg)
When to see a Doctor
Make an appointment with your doctor if you have any signs and symptoms that worry you.